Real Betis are set to be without six players for their crunch Europa League showdown with Rangers this week after they were hit with an injury crisis.
Rangers need to either win in Spain in the final game in the group or match Sparta Prague's result against Aris Limassol in the other match to go through.
Real Betis were already reeling after 80-time capped Portuguese midfielder William Carvalho was ruled out until Christmas after picking up a hamstring injury.
Argentina's World Cup winner Guido Rodríguez is also out for the game through suspension.
And manager Manuel Pellegrini has revealed they have been hit with four other injuries for the visit from Philippe Clement's side on Thursday.
They are also set to be without French playmaker Nabil Fekir, Spanish defender Marc Bartra, Chilean keeper Claudio Bravo, and Senefalese right-back Youssouf Sabaly.
Pellegrini said: "We have a lot of problems with players injured.
"The only positive we can take is that we did tests on Germán Pezzella, after he felt his hamstring, but he is good to play.
"But we are missing important players in a vital period of the season for us."
READ MORE: Clement confirms Rangers striker transfer plan after Danilo injury
Meanwhile, Clement has confirmed Rangers will look to sign a striker in January after the bombshell update that Danilo could require surgery.
The Ibrox boss was coy on any possible transfer incomings next month amid swirling rumours of Lawrence Shankland and Alfredo Morelos pitching up in Govan but admitted a new recruit up front will be among the priorities.
Brazilian forward Danilo will be out until at least the winter break, as well as Tom Lawrence, and fears remain over a longer lay-off with surgery likely required to correct a knee issue.
It means the pair will miss a hectic run of festive fixtures including the Viaplay Cup final against Aberdeen, the final Europa League group stage showdown against Real Betis and the derby against Celtic on December 30.
Why are you making commenting on The National only available to subscribers?
We know there are thousands of National readers who want to debate, argue and go back and forth in the comments section of our stories. We’ve got the most informed readers in Scotland, asking each other the big questions about the future of our country.
Unfortunately, though, these important debates are being spoiled by a vocal minority of trolls who aren’t really interested in the issues, try to derail the conversations, register under fake names, and post vile abuse.
So that’s why we’ve decided to make the ability to comment only available to our paying subscribers. That way, all the trolls who post abuse on our website will have to pay if they want to join the debate – and risk a permanent ban from the account that they subscribe with.
The conversation will go back to what it should be about – people who care passionately about the issues, but disagree constructively on what we should do about them. Let’s get that debate started!
Callum Baird, Editor of The National
Comments: Our rules
We want our comments to be a lively and valuable part of our community - a place where readers can debate and engage with the most important local issues. The ability to comment on our stories is a privilege, not a right, however, and that privilege may be withdrawn if it is abused or misused.
Please report any comments that break our rules.
Read the rules here