US President Joe Biden has confirmed al Qaida leader Ayman al-Zawahri has been killed in a US drone strike in Afghanistan.

He said he hoped the killing of al-Zawahri brought “one more measure of closure” to families of the victims of the September 11 2001 attacks on the United States.

The US President said in an address from the White House: “He will never again, never again, allow Afghanistan to become a terrorist safe haven because he is gone and we’re going to make sure that nothing else happens.

“This terrorist leader is no more.”

Al-Zawahri was tracked down to a home in downtown Kabul by US intelligence agents, Biden said, where he was hiding out with his family. The president approved the operation last week and it was carried out on Sunday.

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Al-Zawahri and the better-known Osama bin Laden plotted the 9/11 attacks that brought many ordinary Americans their first knowledge of al-Qaida.

Bin Laden was killed in Pakistan on May 2, 2011, in operation carried out by US Navy Seals after a nearly decade-long hunt.

The strike was carried out by the CIA, according to five people familiar with the matter who spoke on the condition of anonymity. Neither Biden nor the White House detailed the CIA’s involvement in the strike.

Earlier, White House officials declined to confirm al-Zawahri was killed but noted in a statement that the United States conducted a “successful” counterterrorism operation against a significant al Qaida target, adding that “there were no civilian casualties”.

Biden’s address came as he remains in isolation in the residence while he continues to test positive for Covid-19.

Speaking on August 31, 2021, after the last US troops left Afghanistan and the country fell back under Taliban control, Biden said the US would not give up on the so-called war on terror.

“We will maintain the fight against terrorism in Afghanistan and other countries,” he said.

“We just don’t need to fight a ground war to do it.”

Previewing the strike that would occur 11 months later, Biden said at the time: “We have what’s called over-the-horizon capabilities, which means we can strike terrorists and targets without American boots on the ground — or very few, if needed.”

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A statement from Afghanistan’s Taliban government confirmed the airstrike but did not mention al-Zawahri or any other casualties.

It said the Taliban “strongly condemns this attack and calls it a clear violation of international principles and the Doha Agreement,” the 2020 US pact with the Taliban that led to the withdrawal of American forces.

“Such actions are a repetition of the failed experiences of the past 20 years and are against the interests of the United States of America, Afghanistan, and the region,” the statement said.